What is Retatrutide ?
Retatrutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to semaglutide,tirzepatide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans
Description:
SEMAGLUTIDE & TIRZEPATIDE
GLP-1 agonists were approved by the FDA for weight loss in late 2014. It's a newer class of drugs better known for its ability to improve blood sugar control. These medications were actually designed to treat type II diabetes, but some have also been FDA approved to treat weight loss. The GLP-1 agonists we work with are called Semaglutide & Tirzepatide.
Tirzepatide is dosed at 5-15mg per week
Semaglutide is dosed at 0.5-2.4mg per week
BENEFITS OF GLP-1 AGONISTS
Helps slow food leaving your stomach
Helps prevent your liver from making too much sugar
Helps the pancreas produce more insul when your blood sugar levels are high
Can help control blood glucose
Can reduce hyperglycemia, especially after meals
Can reduce fasting insul and fasting glucose
Can reduce hemoglobin A1c
Can decrease appetite and caloric intake, while inhibiting weight gain
Has been shown to lower triglyceride levels and oxidative stress from high LDL
Has been shown to help induce weight loss in obese patients with higher dosing
Helps decrease leptin and increase leptin sensitivity
Can increase the conversion of white fat to brown fat
FAQ
1.How to get in touch with us?
You can chat with us by Trademanager,Skype,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.
2.Are you a manufacturer or trade company?
We are a professional manufacturer.
3.Can I get a sample?
Yes, free sample can be provided, but shipping cost is covered by your side.
4.What's your MOQ?
It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.
5.When can I get the quotation?
We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.
6.Is there any discount?
Yes, some products are applied for discount, but it depends on the quantity.
7.Can you do OEM for me?
Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.
